Anti -LAMTOR2 Rabbit pAb

價格：在線咨詢

貨號：

KT012215

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	LAMTOR2 rabbit polyclonal
Protein full name	Ragulator complex protein LAMTOR2
Synonyms	Lamtor2, ENDAP, Endosomal adaptor protein p14, MAPBPIP, MAPKSP1AP, P14, ROBLD 3
Immunogen	Recombinant protein corresponding to Mouse LAMTOR2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	Q9JHS3

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 500-1: 2500	brain, lung, stomach
IF	Mouse, Rat	1: 250-1: 500	brain, lung, stomach

Background

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse brain using LAMTOR2 (GB11935) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat brain using LAMTOR2 (GB11935) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse lung using LAMTOR2 (GB11935) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat lung using LAMTOR2 (GB11935) at dilution of 1: 1500
	Immunohistochemistry analysis of paraffin-embedded mouse stomach using LAMTOR2 (GB11935) at dilution of 1: 1500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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