Anti -LAMTOR1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT012209

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	LAMTOR1 rabbit polyclonal antibody
Protein full name	Ragulator complex protein LAMTOR1
Synonyms	Lamtor1, LAMTOR1, C11orf59, PDRO, Ragulator1, p18, p27RF-Rho, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Immunogen	Recombinant protein corresponding to Mouse LAMTOR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	18 kDa
Observed MW.	18 kDa
Uniprot ID	Q6IAA8, Q9CQ22, Q6P791

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, lung, skin

Background

Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.

Images

Western blot analysis of LAMTOR1 (GB11750) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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