Anti -NEAS Rabbit pAb

價格：在線咨詢

貨號：

KT011704

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	NEAS rabbit polyclonal antibody
Protein full name	Spectrin alpha chain, non-erythrocytic 1
Synonyms	Alpha-II spectrin, Alpha Fodrin, SPTAN1, EIEE5, NEAS, SPTA2, spectrin alpha, Non-erythrocytic 1, Non-erythroid alpha chain
Immunogen	Recombinant protein corresponding to Mouse NEAS
Isotype	IgG
Purity	Affinity purification
Predicted MW.	290 kDa
Observed MW.	285 kDa
Uniprot ID	Q13813, P16546, P16086

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	muscle, lung, stomach

Background

The spectrins are a family of widely distributed cytoskeletal proteins which are involved in actin crosslinking, cell adhesion, intercellular communication and cell cycle regulation. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Though a role in cardiac muscle is not well understood, it is likely that alpha II-spectrin is involved in organizing sub-sarcolemmal domains and stabilizing sarcolemmal membranes against the stresses associated with continuous cardiac contraction.

Images

Western blot analysis of α-Fodrin (GB11579) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles
Storage Buffer	PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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