Anti -CITED2 Rabbit pAb

價格：在線咨詢

貨號：

DRF101252

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	CITED2 rabbit polyclonal
Protein full name	Cbp/p300-interacting transactivator 2
Synonyms	MSG-related protein 1, MRG-1, P35srj, Mrg1, Cited2, Msg2
Immunogen	Recombinant protein corresponding to Mouse CITED2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	28 kDa
Observed MW.	28 kDa
Uniprot ID	O35740, Q99MA1

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	brain, heart

Background

CITED2, also named as P35srj, is a cAMP-responsive element-binding protein (CBP)/p300-transactivator, with an ED(Glu/Asp)-rich C-terminal domain that acts as an important modulator in the development of the heart .It is proposed to be a negative regulator of HIF-1α through its competitive binding to the CH1 domain of CBP/p300, which mediated signaling and to a decrease in HIF-1-responsive genes such as VEGF. In addition, it is also a co-activator of the transcriptional activity of the TFAP2 isoform, which is an extensively expressed nuclear protein with functions in embryogenesis, inflammation, and stress responses.

Images

Western blot analysis of CITED2 (GB111129) at dilution of 1: 1000
Lane 1: Mouse brain tissue lysate
Lane 2: Rat heart tissue lysate
Lane 3: Rat brain tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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