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Anti -AP-2 complex subunit alpha-1 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101240
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Ap2a1 rabbit polyclonal

Protein full name

AP-2 complex subunit alpha-1

Synonyms

100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Ap2a1, Adtaa, Clapa1

Immunogen

Recombinant protein corresponding to Mouse Ap2a1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

108 kDa

Observed MW.

108 kDa

Uniprot ID

O95782




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

HEK293, HeLa, A431 , 293T, HepG2




Background


AP2A1 encodes adaptor protein complex 2 (AP-2) subunit alpha-1, which is a 100 kDa coated vesicle protein. Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes also play a pivotal role in the cargo selection by recognizing the sorting signals within the cytoplasmic tail of integral membrane proteins. AP-2 is involved in clathrin-dependent endocytosis.




Images


Western blot analysis of Ap2a1 (GB111116) at dilution of 1: 1000
Lane 1: HEK293 cell lysate
Lane 2: Hela cell lysate
Lane 3: A431 cell lysate
Lane 4: 293T cell lysate
Lane 5: HepG2 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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