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Anti -Prohibitin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101163
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Prohibitin rabbit polyclonal

Protein full name

Prohibitin

Synonyms

B-cell receptor-associated protein 32,

C-BAP 32, Phb, PHB, HEL-215, HEL-S-54e, PHB1, prohibitin

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Prohibitin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

30 kDa

Observed MW.

30 kDa

Uniprot ID

P35232, P67778, P67779




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, brain




Background


Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription. Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .




Images




image.png



Western blot analysis of Prohibitin (GB111045) at dilution of 1: 1000

Lane 1: MCF7 cell lysate

Lane 2: Hela cell lysate

Lane 3: Jurkat cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse heart tissue lysate

Lane 7: Mouse brain tissue lysate

Lane 8: Rat heart tissue lysate

Lane 9: Rat brain tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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