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Anti -COX2 / Cyclooxygenase 2 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101154
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Cyclooxygenase 2 rabbit polyclonal

Protein full name

Prostaglandin G/H synthase 2

Synonyms

PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2,hCox-2, prostaglandin-endoperoxide synthase 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Human Cyclooxygenase 2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

74 kDa

Uniprot ID

Q05769, P35355




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

Inflammatory spleen, inflammation lung, thymus




Background


Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression.It is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS, a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.




Images


image.png

Western blot analysis of Cyclooxygenase 2 (GB111037) at dilution of 1: 1000

Lane 1: Mouse Inflammatory spleen tissue lysate

Lane 2: Mouse inflammation lung tissue lysate

Lane 3: Mouse thymus tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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