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Anti -CD40 Rabbit pAb
價(jià)格：
在線咨詢(xún)
貨號(hào)：
DRF101150
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
M/R
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
CD40 rabbit polyclonal |
|
Protein full name |
Tumor necrosis factor receptor superfamily member 5 |
|
Synonyms |
B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5, CDw40, GP39, HIGM1, IGM, IMD3, TBAM |
|
Immunogen |
Recombinant protein corresponding to Mouse CD40 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
32 kDa |
|
Observed MW. |
45 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
spleen, thymus, lymph nodes |
Background
CD40, also named as TNFRSF5 and Bp50, is a receptor for TNFSF5/CD40LG. It is a member of the TNFR super family and is responsible for the efficient activation of cell-mediated and humoral immune responses via activated T cells and B cells respectively. Defects in CD40 lead to hyper-IgM immunodeficiency syndrome type 3 (HIGM3) . This is an autosomal recessive disorder that includes the inability of B cells to undergo isotype switching, a key step in the final differentiation of the humoral immune response, and an inability to mount an antibody-specific immune response.
Images
|
|
Western blot analysis of CD40 (GB111033) at dilution of 1: 1000 Lane 1: A20 cell lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse lymph nodes tissue lysate Lane 4: Mouse thymus tissue lysate Lane 5: Rat lymph nodes tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室