Anti -5HT2C Receptor Rabbit pAb

價格：在線咨詢

貨號：

DRF101117

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	5HT2C Receptor rabbit polyclonal
Protein full name	5-hydroxytryptamine receptor 2C
Synonyms	5-ht-1c receptor, 5HT1C, 5HT2C, 5HTR2C, G protein-coupled, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C, Htr1c, HTR2C, serotonin 1c receptor, serotonin 2c receptor, Serotonin 5-HT-2C receptor
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse 5HT2C Receptor
Isotype	IgG
Purity	Affinity purification
Predicted MW.	52 kDa
Observed MW.	52 kDa
Uniprot ID	P34968, P08909

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	brain, cerebral cortex, , cerebellum, hippocampus

Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C.

Images

Western blot analysis of 5HT2C (GB111002) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cerebral cortex tissue lysate

Lane 3: Mouse cerebellum tissue lysate

Lane 4: Mouse hippocampus tissue lysate

Lane 5: Rat brain tissue lysate

Lane 6: Rat cortex tissue lysate

Lane 7: Rat cerebellum tissue lysate.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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