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Anti -Cyclin D1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF10194
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Cyclin D1 rabbit polyclonal

Protein full name

G1/S-specific cyclin-D1

Synonyms

CCND1, BCL1, D11S287E, PRAD1, U21B31, cyclin D1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Cyclin D1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

33 kDa

Observed MW.

34 kDa

Uniprot ID

P25322



Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, kidney, brain



Background



The protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDKs (Cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.




Images



圖片 1.png

Western blot analysis of Cyclin D1 (GB11079) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Mouse kidney tissue lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Rat lung tissue lysate

Lane 6: Rat kidney tissue lysate

Lane 7: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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