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Anti -COX2 / Cyclooxygenase 2 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
DRF10192
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

COX2 rabbit polyclonal

Protein full name

Prostaglandin G/H synthase 2

Synonyms

PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse COX2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

74 kDa

Uniprot ID

Q05769, P35355, P35354




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1:500-1:1000

inflammatory lung,

colon cancer, Raw264.7





Background



Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.




Images



blob.png

Western blot analysis of COX2 (GB11077-2) at dilution of 1: 1000.

Lane 1: Raw264.7 cell lysate

Lane 2: B16 cell lysate

Lane 3: Human colon cancer tissue lysate

Lane 4: Mouse myeloma tissue lysate

Lane 5: Mouse inflammatory lung tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat inflammatory lung tissue lysate

Lane 8: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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