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Product Information
Description |
c-Kit rabbit polyclonal |
Protein full name |
Mast/stem cell growth factor receptor Kit |
Synonyms |
KIT, C-Kit, CD117, PBT, SCFR, KIT proto-oncogene receptor tyrosine kinase |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse c-Kit |
Isotype |
IgG |
Subcellular location |
|
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
IHC |
Human, Mouse, Rat |
1: 200-1: 1000 |
tonsil, liver, colon |
IF |
Human, Mouse, Rat |
1: 200-1: 1000 |
tonsil, liver, colon |
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
|
Immunohistochemistry analysis of paraffin-embedded human tonsil using c-Kit (GB11073-2) at dilution of 1:400. |
Immunohistochemistry analysis of paraffin-embedded human liver using c-Kit (GB11073-2) at dilution of 1:400. |
|
Immunohistochemistry analysis of paraffin-embedded rat colon using c-Kit (GB11073-2) at dilution of 1:400. |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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