Anti -CD11c Rabbit pAb

價格：在線咨詢

貨號：

DRF10177

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

M,H/M/R,H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD11c rabbit polyclonal
Protein full name	Integrin alpha-X
Synonyms	ITGAX, CD11C, SLEB6, integrin subunit alpha X
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD11c
Isotype	IgG
Predicted MW.	129 KDa
Observed MW.	150 KDa
Purity	Affinity purification
Subcellular location	Membrane
Uniprot ID	P20702, Q9QXH4

Applications

applications	species	dilution	Positive tissue
WB	Mouse	1: 500-1: 1000	thymus, spleen, inflammatory lung
IHC	Human, Mouse, Rat	1: 200-1: 400	tonsil, inflammatory lung, lung, splenitis
IF	Human, Mouse, Rat	1: 200-1: 400	pneumonia, spleen

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Images

	Western blot analysis of CD11c(GB11059) at dilution of 1:1000 Lane 1: Raw264.7 cell lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse inflammatory lung tissue lysate Lane 4: Mouse thymus tissue lysate
	Immunohistochemistry analysis of paraffin-embedded human tonsil using CD11c(GB11059) at dilution of 1: 400
	Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using CD11c(GB11059) at dilution of 1: 400
	Immunohistochemistry analysis of paraffin-embedded mouse lung using CD11c(GB11059) at dilution of 1: 400
	Immunohistochemistry analysis of paraffin-embedded mouse splenitis using CD11c(GB11059) at dilution of 1: 400
	Immunofluorescent analysis of paraformaldehyde-fixed rat inflammatory lung using CD11c(GB11059) at dilution of 1: 400
	Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using CD11c(GB11059) at dilution of 1: 400

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice.	International Immunopharmacology	33182020	IHC
2	MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB.	JCI Insight	32213710	IHC

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