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Anti -VEGFA Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
DRF10171
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
H/M/R
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
VEGFA rabbit polyclonal |
|
Protein full name |
Vascular endothelial growth factor A |
|
Synonyms |
VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse VEGFA |
|
Isotype |
IgG |
|
Predicted MW. |
25 kDa |
|
Observed MW. |
43 kDa |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
P15692, Q00731, P16612 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1:500-1:1000 |
B16, liver cancer, kidney |
Background
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .
Images
|
|
Western blot analysis of VEGFA (GB11034B) at dilution of 1: 1000. Lane 1: B16 cell lysate Lane 2: Human nasopharyngeal carcinoma tissue lysate Lane 3: Human liver cancer tissue lysate Lane 4: Human liver tissue lysate Lane 5: Mouse kidney tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat kidney tissue lysate Lane 8: Rat brain tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室