Anti -p38 Rabbit pAb

價格：在線咨詢

貨號：

KT012255

產(chǎn)品規(guī)格：

100ul

Applications：

IHC/IF

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	P38 rabbit polyclonal
Protein full name	Mitogen-activated protein kinase 14
Synonyms	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2,PRKM14,PRKM15, RK, SAPK2A,p38,p38ALPHA, mitogen-activated protein kinase 14
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse P38
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	Q16539,P47811,P70618

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 1000-1: 2000	kidney, lung, lung cancer, testis

Background

MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such asproliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response.

Images

	Immunohistochemistry of paraffin embedded human lung cancer using P38 at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded mouse kidney using P38 at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded mouse lung using P38at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded mouse testis using P38 at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded rat kidney using P38 at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded rat lung using P38 at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded rat testis using P38at dilution of 1:1000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.

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