Anti -Caspase-9 Rabbit pAb

價格：在線咨詢

貨號：

KT012188

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Caspase-9 rabbit polyclonal antibody
Protein full name	Caspase-9
Synonyms	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9
Immunogen	Recombinant protein corresponding to Mouse Caspase9
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Predicted MW.	50 kDa
Observed MW.	35/46 kDa
Uniprot ID	Q8C3Q9

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 800-1: 1000	heart, brain, skeletal muscle

Background

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increased in the response of cells to genotoxic stress and ABL1/c-Abl activation (By similarity).

Images

Picture 1.png

Western blot analysis of Caspase9 (GB11053-1) at dilution of 1: 800

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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