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Anti -GPNMB Rabbit pAb

價格: 在線咨詢
貨號:
KT012047
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

GPNMB rabbit polyclonal antibody

Protein full name

Transmembrane glycoprotein NMB

Synonyms

DC-HIL, Dendritic cell-associated transmembrane protein, Osteoactivin, Gpnmb, Dchil, Hgfin, Nmb

Immunogen

Recombinant protein corresponding to Mouse GPNMB

Isotype

IgG

Purity

Affinity purification

Predicted MW.

64 kDa

Observed MW.

64 kDa

Uniprot ID

Q14956, Q99P91, Q6P7C7




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, liver, heart



Background

GPNMB also known as HGFIN, osteoactivin, and DC-HIL, is a type I membrane glycoprotein involved in various biological processes, including inflammation, invasion and metastasis of malignant tumors, cell differentiation, and tissue regeneration. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB acts as an osteogenic factor that stimulates osteoblast differentiation in vivo and in vitro.




Images


Picture 1.png Western blot analysis of GPNMB (GB111475) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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