Rab27a, Rab27, Ras-related protein Rab-27A, Ras-related protein Rab27A
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse RAB27A
Isotype
IgG
Purity
Affinity purification
Predicted MW.
25 kDa
Observed MW.
28 kDa
Uniprot ID
Q9ERI2, P23640
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 500-1: 1000
liver, ovary, kidney
Background
Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.
Images
Western blot analysis of RAB27A (GB111106) at dilution of 1: 500
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.