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Product Information
Description |
FOXP3 rabbit polyclonal antibody |
Protein full name |
Forkhead box protein P3 |
Synonyms |
FOXP3, AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3 |
Immunogen |
Recombinant protein corresponding to Mouse FOXP3 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
47 kDa |
Observed MW. |
47 kDa |
Uniprot ID |
Q99JB6, Q9BZS1 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
inflammatory spleen, thymus gland |
Background
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells.Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.
Images
|
Western blot analysis of FOXP3 (GB11093-1) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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