Anti -Asialoglycoprotein Receptor 1/HL-1 Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT011927

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	ASGR1 rabbit polyclonal antibody
Protein full name	Asialoglycoprotein receptor 1
Synonyms	ASGP-R 1, Hepatic lectin 1, HL-1, mHL-1, Asgr1, Asgr
Immunogen	Recombinant protein corresponding to Mouse ASGR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	33 kDa
Observed MW.	42 kDa
Uniprot ID	P34927, P02706

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	liver

Background

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

Images

Picture 1.png

Western blot analysis of ASGR1 (GB111336) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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