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Product Information
Description |
S100 beta rabbit polyclonal antibody |
Protein full name |
Protein S100-B |
Synonyms |
S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B, S100β |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100B |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Cytoplasm |
Uniprot ID |
P50114, P04631, P04271 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 500-1: 4000 |
brain |
Background
S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
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Immunohistochemistry of paraffin embedded mouse brain using S100B (GB11359) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using S100B (GB11359) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using S100B (GB11359) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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