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Anti -Kir2.1/BIK Rabbit pAb

價(jià)格: 在線(xiàn)咨詢(xún)
貨號(hào):
KT011465
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M,R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

BIK rabbit polyclonal antibody

Protein full name

Inward rectifier potassium channel 2

Synonyms

Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2, Kcnj2, Irk1

Immunogen

Recombinant protein corresponding to Mouse BIK

Isotype

IgG

Purity

Affinity purification

Predicted MW.

48 kDa

Observed MW.

55 kDa

Uniprot ID

P35561, Q64273




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

brain




Background


KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3).




Images


Picture 1.png

Western blot analysis of KIR2.1 (GB111433) at dilution of 1: 500




Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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