Anti -SYT1 Rabbit pAb

價格：在線咨詢

貨號：

KT011457

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC

Species：

M,R|H

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	SYT1 rabbit polyclonal
Protein full name	Synaptotagmin-1
Synonyms	Synaptotagmin I, SytI, p65, DKFZp781D2042, FLJ42519, SVP65, Syt2
Immunogen	Recombinant protein corresponding to Mouse SYT1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell Membrane
Predicted MW.	47 kDa
Observed MW.	60 kDa
Uniprot ID	P21579, P46096, P21707

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	brain, cortex, hippocampus
IHC	Human	1: 1000-1: 4000	lung cancer

Background

This protein calcium sensor that participates in triggering neurotransmitter release at the synapse . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.

Images

Western blot analysis of SYT1 (GB111130)

at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cortex tissue lysate

Lane 3: Mouse hippocampus tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat cortex tissue lysate

Lane 6: Rat hippocampus tissue lysate

Immunohistochemistry analysis of paraffin-embedded human lung cancer using SYT1 (GB111130) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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