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Anti -5HT2A Receptor Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011454
產(chǎn)品規(guī)格:
100 μL
Applications:
WB | IHC | IF
Species:
M,R | H,M,R| H,M,R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

5HT2A Receptor rabbit polyclonal

Protein full name

5-hydroxytryptamine receptor 2A

Synonyms

5-HT-2, 5-HT-2A, Serotonin receptor 2A, Htr2a, Htr2, serotonin 5-HT-2 receptor, 5 hydroxytryptamine receptor 2A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse 5HT2A

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Predicted MW.

53 kDa

Observed MW.

53 kDa

Uniprot ID

P28223, P35363, P14842




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

cerebral cortex, brain, colon, cerebellum

IHC

Human, Mouse, Rat

1: 200-1: 800

colon cancer, small intestine

IF

Human, Mouse, Rat

1: 100-1: 2000

colon cancer, small intestine




Background


This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.




Images


image.png

Western blot analysis of 5HT2A (GB111001)

at dilution of 1: 1000

Lane 1: Mouse cerebral cortex tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse colon tissue lysate

Lane 4: Mouse cerebellum tissue lysate

Lane 5: Rat cerebral cortex tissue lysate

Lane 6: Rat brain tissue lysate

Lane 7: Rat colon tissue lysate

Lane 8: Rat cerebellum tissue lysate


image.png

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using 5HT2A (GB111001) at dilution of 1: 400

image.png

Immunohistochemistry analysis of paraffin-embedded mouse small intestine using 5HT2A (GB111001) at dilution of 1: 400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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