Anti -ZAP70 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101936

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	ZAP70 rabbit polyclonal
Protein full name	Tyrosine-protein kinase ZAP-70
Synonyms	70 kDa zeta-chain associated protein, Srk, Syk-related tyrosine kinase, Zap70, Zap-70
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse ZAP70
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Cytoplasm
Uniprot ID	A0A0R4J8U1

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 650-1: 1300	spleen
IF	Mouse, Rat	1: 1000-1: 2000	spleen, lymph, thymus

Background

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Images

	Immunohistochemistry analysis of paraffin-embedded rat spleen using ZAP70 (GB111109) at dilution of 1: 1300
	Immunofluorescent analysis of paraffin-embedded rat spleen using ZAP70 (GB111109) at dilution of 1: 2000
	Immunofluorescent analysis of paraffin-embedded rat lymph using ZAP70 (GB111109) at dilution of 1: 1300
	Immunofluorescent analysis of paraffin-embedded rat thymus using ZAP70 (GB111109) at dilution of 1: 1300

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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