Anti -KMT3C/SMYD2 Rabbit pAb

價格：在線咨詢

貨號：

KT012155

產(chǎn)品規(guī)格：

Applications：

IHC/IF

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	KMT3C/SMYD2 rabbit polyclonal antibody
Protein full name	N-lysine methyltransferase SMYD2
Synonyms	Histone methyltransferase SMYD2, SET and MYND domain-containing protein 2, Smyd2, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2
Immunogen	Recombinant protein corresponding to Mouse SMYD2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Uniprot ID	Q8R5A0, Q7M6Z3

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 1000-1: 4000	Bone fibroids, brain, heart, Skeletal muscle

Background

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.

Images

	Immunohistochemistry of paraffin embedded mouse heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded mouse brain using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded mouse Skeletal muscle using SMYD2 (GB111583) at dilution of 1:1000 (400x lens)
	Immunofluorescence of paraffin embedded rat Bone fibroids using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)
	Immunofluorescence of paraffin embedded rat heart using SMYD2 (GB111583) at dilution of 1:2000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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