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Anti -TNNC1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011888
產品規(guī)格:
100ul
Applications:
WB|IHC/IF
Species:
M/R,M/R
購買數(shù)量:
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產品詳情 操作說明 注意事項

Product Information


Description

TNNC1 rabbit polyclonal antibody

Protein full name

Troponin C, slow skeletal and cardiac muscles

Synonyms

Tnnc1, TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin C type 1, Troponin C1, Slow skeletal and cardiac type

Immunogen

Recombinant protein corresponding to Mouse TNNC1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Predicted MW.

18 kDa

Observed MW.

18 kDa

Uniprot ID

P19123




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

heart, lung, skeletal muscle, liver

IHC/IF

Mouse, Rat

1: 800-1: 3000

heart, lung, myocardial infarction, Skeletal muscle




Background


Troponin I (TnI), troponin T (TnT) , troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).




Images


Western blot analysis of Tncc (GB111243) at dilution of 1: 500

Immunohistochemistry of paraffin embedded mouse myocardial infarction using TnCC (GB111243) at dilution of 1: 800 (400x lens)

Immunohistochemistry of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 800 (400x lens)

Immunofluorescence of paraffin embedded mouse lung using TnCC (GB111243) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded mouse skeletal muscle using TnCC (GB111243) at dilution of 1: 1600 (400x lens)

Immunofluorescence of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 1600 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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