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Anti -p27 KIP 1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011811
產(chǎn)品規(guī)格:
Applications:
IHC/IF
Species:
H,M,R
購買數(shù)量:
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Product Information


Description

p27 KIP1 rabbit polyclonal antibody

Protein full name

Cyclin-dependent kinase inhibitor 1B

Synonyms

CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1, cyclin-dependent kinase inhibitor 1B, cyclin dependent kinase inhibitor 1B

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse p27 KIP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm, Endosome

Uniprot ID

P46527, P46414




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 100-1: 500

colon, heart, hepatitis, nephritis, pneumonia, Skeletal muscle, stomach, subcutaneous transplant tumor




Background


Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.




Images



Picture 1.png Immunohistochemistry of paraffin embedded human stomach using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 2.png Immunohistochemistry of paraffin embedded human subcutaneous transplant tumor using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 3.png Immunohistochemistry of paraffin embedded mouse Skeletal muscle using P27 (GB11154) at dilution of 1:500 (400x lens)
Picture 4.png Immunohistochemistry of paraffin embedded rat Skeletal muscle using P27 (GB11154) at dilution of 1:500 (400x lens)
Picture 5.png Immunofluorescence of paraffin embedded mouse heart using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 6.png Immunofluorescence of paraffin embedded rat colon using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 7.png Immunofluorescence of paraffin embedded rat hepatitis using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 8.png Immunofluorescence of paraffin embedded rat nephritis using P27 (GB11154) at dilution of 1:400 (400x lens)
Picture 9.png Immunofluorescence of paraffin embedded rat pneumonia using P27 (GB11154) at dilution of 1:400 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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