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Anti -Cyclin D3/CCND3 Rabbit pAb

價格: 在線咨詢
貨號:
KT011760
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H,M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Cyclin D3 rabbit polyclonal antibody

Protein full name

G1/S-specific cyclin-D3

Synonyms

Ccnd3, Cyl-3, CyclinD3, D3 type cyclin, G1 S specific cyclin D3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

32 kDa

Observed MW.

32 kDa

Uniprot ID

P30281, P30282, P48961




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, kidney




Background


Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.




Images


Picture 1.png

Western blot analysis of Cyclin-D2 (GB111250) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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