Anti -AFG3L2 Rabbit pAb

價格：在線咨詢

貨號：

KT011755

產(chǎn)品規(guī)格：

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	AFG3L2 rabbit polyclonal antibody
Protein full name	AFG3-like protein 2
Synonyms	AFG3 like protein 2, AFG3L2, Paraplegin like protein, SCA28, Spinocerebellar ataxia 28, AFG3 ATPase family gene 3 like 2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse AFG3L2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	90 kDa
Observed MW.	90 kDa
Uniprot ID	Q9Y4W6, Q8JZQ2

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 1000-1: 2000	liver, brain, kidney

Background

AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. Human AFG3L2 is an 80-kDa protein encoded by a 17-exon gene and highly and selectively expressed in human cerebellar Purkinje cells and it can exsit as a truncated 65 kDa protein. Defects in AFG3L2 are the cause of spinocerebellar ataxia type 28 (SCA28) and spastic ataxia autosomal recessive type 5 (SPAX5).

Images

Western blot analysis of AFG3L2 (GB113859) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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