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Anti -HEC1/HEC Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011748
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M,R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

HEC1 rabbit polyclonal antibody

Protein full name

Kinetochore protein NDC80 homolog

Synonyms

Kinetochore protein Hec1, Hec1, Kntc2, Kinetochore-associated protein 2, Ndc80

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HEC1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

74 kDa

Observed MW.

74 kDa

Uniprot ID

Q9D0F1




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

testis, spleen




Background


Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.




Images


Picture 1.png

Western blot analysis of NDC80 (GB111227) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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