服務(wù)熱線
400-1016-218
全國(guó)統(tǒng)一服務(wù)熱線
400-1016-218
科研好幫手 專業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁(yè) > 產(chǎn)品中心 > 抗體 >>一抗 >>細(xì)胞周期 >> Anti -HEC1/HEC Rabbit pAb
Product Information
Description |
HEC1 rabbit polyclonal antibody |
Protein full name |
Kinetochore protein NDC80 homolog |
Synonyms |
Kinetochore protein Hec1, Hec1, Kntc2, Kinetochore-associated protein 2, Ndc80 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse HEC1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
74 kDa |
Observed MW. |
74 kDa |
Uniprot ID |
Q9D0F1 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
testis, spleen |
Background
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.
Images
|
Western blot analysis of NDC80 (GB111227) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬(wàn)物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室