Anti -Arp3 Rabbit pAb

價格：在線咨詢

貨號：

KT011626

產(chǎn)品規(guī)格：

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Arp3 rabbit polyclonal antibody
Protein full name	Actin-related protein 3
Synonyms	Actin-like protein 3, Actr3, Arp3, ACTR3; ARP3 actin-related protein 3 homolog
Immunogen	Recombinant protein corresponding to Mouse Arp3
Isotype	IgG
Purity	Affinity purification
Predicted MW.	47 kDa
Observed MW.	47 kDa
Uniprot ID	P61158, Q99JY9, Q4V7C7

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, spleen

Background

ARP3 (also known as ACTR3) is a major constituent of the ARP2/3 complex that is necessary for nucleating actin polymerization at filament branches. ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). Plays a role in ciliogenesis.

Images

Western blot analysis of ARP3 (GB111478) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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