Anti -Amyloid beta precursor protein Rabbit pAb

價格：在線咨詢

貨號：

KT011562

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

HMR/MR/MR

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Amyloid beta precursor protein rabbit polyclonal
Protein full name	Amyloid beta A4 protein
Synonyms	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, amyloid beta precursor protein, preA4, β-Amyloid
Immunogen	Recombinant protein corresponding to Mouse Amyloid beta precursor protein (APP)
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane
Predicted MW.	86 kDa
Observed MW.	100-140 kDa
Uniprot ID	P12023, P08592

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 300-1: 800	brain, cerebellum
IHC	Mouse, Rat	1: 500-1: 1000	brain
IF	Mouse, Rat	1: 500-1: 1000	brain

Background

Functions as a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis.

Images

	Western blot analysis of APP(GB11307) at dilution of 1: 800
	Western blot analysis of APP(GB11307) at dilution of 1: 800
	Immunohistochemistry analysis of paraffin-embedded mouse brain using APP(GB11307) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded rat brain using APP(GB11307) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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