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Anti -TAU Rabbit pAb

價格: 在線咨詢
貨號:
KT011522
產(chǎn)品規(guī)格:
100 μL
Applications:
WB/IHC
Species:
HMR/HM
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description TAU rabbit polyclonal
Protein full name Microtubule-associated protein tau
Synonyms Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, DDPAC, FTDP 17, MAPTL, RNPTAU, PPP1R103, Paired helical filament-tau
Immunogen KLH conjugated Synthetic peptide
corresponding to Human TAU
Isotype IgG
Purity Affinity purification
Subcellular location Cytoplasm, Cell membrane
Predicted MW. 79 kDa
Observed MW. 50-80 kDa
Uniprot ID P10636, P10637, P19332




Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 2000-1: 4000 brain, cortex, spinal cord, hippocampus
IHC Human, Mouse 1: 3000-1: 5000 gliomas, brain




Background

Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.




Images



Western blot analysis of TAU (GB111608)
at dilution of 1: 2000
Lane 1: Human glioma cell lysate
Lane 2: Mouse brain tissue lysate
Lane 3: Mouse cortex tissue lysate
Lane 4: Mouse hippocampus tissue lysate
Lane 5: Mouse spinal cord tissue lysate
Lane 6: Rat brain tissue lysate
Lane 7: Rat cortex tissue lysate
Lane 8: Rat hippocampus tissue lysate

Immunohistochemistry analysis of paraffin-embedded human gliomas using TAU (GB111608) at dilution of 1: 3000
Immunohistochemistry analysis of paraffin-embedded mouse brain using TAU (GB111608) at dilution of 1: 3000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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