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Anti -CD27 Rabbit pAb
價(jià)格：
在線咨詢(xún)
貨號(hào)：
DRF101871
產(chǎn)品規(guī)格：
100 μL
Applications：
Species：
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
CD27 rabbit polyclonal |
|
Protein full name |
CD27 antigen |
|
Synonyms |
CD27, S152, S152. LPFS2, T14, TNFRSF7, Tp55, CD27 molecule |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD27 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Membrane |
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
positive tissue |
|
IHC |
Rat |
1: 500-1: 2000 |
spleen |
Background
CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Images
|
Immunohistochemistry analysis of paraffin-embedded rat spleen using CD27 (GB11582) at dilution of 1: 500
|
Storage
| Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室