Anti -CD11B Rabbit pAb

價格：在線咨詢

貨號：

DRF101861

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD11B rabbit polyclonal
Protein full name	Integrin alpha-M
Synonyms	CD11B, CR 3 alpha chain, CR3A, ITGAM, MAC 1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6
Immunogen	Recombinant protein corresponding to Human CD11B
Isotype	IgG
Purity	Affinity purification
Predicted MW.	126 kDa
Observed MW.	170 kDa
Uniprot ID	P05555

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	lung, spleen

Background

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits . CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens . CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1.

Images

Western blot analysis of CD11B

at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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