Anti -TLR4 Mouse mAb

價格：在線咨詢

貨號：

DRF101763

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	TLR4 mouse monoclonal
Protein full name	Toll-like receptor 4
Synonyms	TLR4, ARMD10, CD284, TLR-4, TOLL, toll like receptor 4
Immunogen	Recombinant protein corresponding to Mouse TLR4
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	Q9QUK6, Q9QX05

Applications

applications	species	dilution	Positive tissue
IHC	Mouse, Rat	1: 500-1: 1000	spleen
IF	Mouse, Rat	1: 500-1: 1000	spleen

Background

TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system.It is most well known for recognizinglipopolysaccharide (LPS), a component present in many Gram-negative bacteria (e.g. Neisseria spp.) and selectGram-positive bacteria. Its ligands also include several viral proteins, polysaccharide, and a variety of endogenous proteins such as low-density lipoprotein, beta-defensins, and heat shock protein.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse spleen using TLR4 (GB12186) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat spleen using TLR4 (GB12186) at dilution of 1:1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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