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Anti -Dectin-1 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101743
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Dectin-1 rabbit polyclonal

Protein full name

C-type lectin domain family 7 member A

Synonyms

Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CD369, Clec7a, Bgr, Clecsf12, Dectin1

Immunogen

Recombinant protein corresponding to Mouse Dectin-1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

27 kDa

Observed MW.

38 kDa

Uniprot ID

Q9BXN2, Q6QLQ4




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, thymus, liver




Background


CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response.




Images


圖片 1.png

Western blot analysis of Dectin-1 (GB111816)

at dilution of 1: 1000

Lane 1: U2OS cell lysate

Lane 2: Mouse spleen tissue lysate

Lane 3: Mouse thymus tissue lysate

Lane 4: Mouse liver tissue lysate

Lane 5: Rat thymus tissue lysate

Lane 6: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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