Anti -Factor XIIIa Mouse mAb

價格：在線咨詢

貨號：

DRF101536

產品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數量：

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產品詳情操作說明注意事項

Product Information

Gene Name	F13A1 F13A
Protein Name	Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain)
Human Gene Id	2162
Human Swiss Prot No	P00488
Immunogen	Synthesized peptide derived from human Factor XIIIa
Specificity	This antibody detects endogenous levels of human Factor XIIIa
Source	Mouse/IgG2a, Kappa
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Applications

Applications	Species	Dilution
IHC、IF	Human	1:200-1:500

Background

coagulation factor XIII A chain(F13A1) Homo sapiens This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor,

Images

	Immunohistochemical analysis of paraffin-embedded Malignant fibrous histiocytoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Appendix. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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