Anti -Cytokeratin 6 Mouse mAb

價格：在線咨詢

貨號：

DRF101519

產(chǎn)品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Gene Name	KRT6A K6A KRT6D
Protein Name	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Human Gene Id	5853
Human Swiss Prot No	P02538
Immunogen	Synthesized peptide derived from human Cytokeratin 6
Specificity	This antibody detects endogenous levels of human Cytokeratin 6
Source	Mouse/IgG1, Kappa
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Applications

Applications	Species	Dilution
IHC、IF	Human	1:200-1:500

Background

keratin 6A(KRT6A) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathoge

Images

	Immunohistochemical analysis of paraffin-embedded Lung squamous cell carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Lung squamous cell carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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