Anti -CD105 Mouse mAb

價格：在線咨詢

貨號：

DRF101477

產品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數量：

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產品詳情操作說明注意事項

Product Information

Gene Name	ENG END
Protein Name	Endoglin (CD antigen CD105)
Human Gene Id	2022
Human Swiss Prot No	P17813
Immunogen	Synthesized peptide derived from human CD105(Endoglin)
Specificity	This antibody detects endogenous levels of human CD105(Endoglin)
Source	Mouse/IgG1, Kappa
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Applications

Applications	Species	Dilution
IHC、IF	Human	1:200-1:500

Background

Endoglin encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in Endoglin cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Endoglin may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for Endoglin.

Images

	Immunohistochemical analysis of paraffin-embedded Placenta. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.
	Immunohistochemical analysis of paraffin-embedded Renal clear cell carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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