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- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室
Anti -Lamin A + Lamin C Mouse mAb
價(jià)格：
在線咨詢(xún)
貨號(hào)：
DRF101384
產(chǎn)品規(guī)格：
100 μL
Applications：
Species：
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
Lamin A + Lamin C mouse monoclonal |
|
Protein full name |
Prelamin-A/C |
|
Synonyms |
Lamin-A/C, Lmna, Lmn1, Cardiomyopathy dilated 1A (autosomal dominant), LGMD1B, LFP, LMNA, Renal carcinoma antigen NYREN32 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Lamin A + Lamin C |
|
Isotype |
IgG2b |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus |
|
Predicted MW. |
74 kDa |
|
Observed MW. |
74 kDa |
|
Uniprot ID |
P02545, P48678, P48679 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
lung |
|
IHC |
Human, Rat |
1: 1500-1: 3000 |
cervical cancer,lung cancer, ovarian cancer, liver |
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy.
Images
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Western blot analysis of Lamin A/C (GB122400) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded human cervical cancer using Lamin A/C (GB122400) at dilution of 1: 3000 |
|
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using Lamin A/C (GB122400) at dilution of 1: 3000 |
|
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Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using Lamin A/C (GB122400) at dilution of 1: 3000 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse liver using Lamin A/C (GB122400) at dilution of 1: 3000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat liver using Lamin A/C (GB122400) at dilution of 1: 3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室