Anti -Cytokeratin 1 Mouse mAb

價格：在線咨詢

貨號：

DRF101322

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Cytokeratin 1 mouse monoclonal
Protein full name	Keratin, type II cytoskeletal 1
Synonyms	67 kDa cytokeratin, Cytokeratin-1, Keratin-1, CK-1, K1, Type-II keratin Kb1, Krt1, Krt2-1, EHK1, Keratin type II cytoskeletal 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Human Cytokeratin 1
Isotype	IgG1
Purity	Affinity purification
Predicted MW.	66 kDa
Observed MW.	66 kDa
Uniprot ID	P04264, P04104, Q6IMF3

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human	1: 500-1: 1000	A-431

Background

Cytokeratin 1 is a heterotetramer of two type I as well as two type II keratins localized in the cell membrane and is generally associated with keratin-10 . It has been suggested to regulate the activity of kinases such as PKC/SRC via binding to integrin beta-1 and the receptor of activated protein kinase C. Cytokeratin 1 and its heterodimer partner KRT10 are the major constituents of 4 intermediate filament cytoskeleton in suprabasal epidermis/keratinocytes, and their upregulation precedes expression of filaggrin and cornified envelope proteins.

Images

Western blot analysis of CK1 (GB121017)

at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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