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Anti -Desmin Mouse mAb

價格: 在線咨詢
貨號:
DRF101309
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Desmin mouse monoclonal

Protein full name Desmin

Synonyms

DES, CSM1, CSM2, LGMD2R, desmin
Immunogen

Recombinant protein corresponding to Mouse desmin

Isotype IgG
Purity Affinity purification
Predicted MW.

54 kDa

Observed MW.

54 kDa

Subcellular location

Cytoplasm,Cell membrane

Uniprot ID P31001,P48675




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000-1: 2000

Heart,C2C12 cell

IHC

Mouse, Rat

1: 200-1: 1000

Heart,skeletal muscle

IF

Mouse, Rat

1: 200-1: 1000

Heart,skeletal muscle




Background



Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures . May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.




Images



GB12081.png

Western blot analysis of Desmin (GB12081) at dilution of 1:1000.

Lane 1:C2C12 cell lysate

Lane 2:Hela cell lysate

Lane 3:Raw264.7 cell lysate

Lane 4:Mouse heart tissue lysate

Lane 5:Mouse spleen tissue lysate

Lane 6:Mouse lung tissue lysate

Lane 7:Rat heart tissue lysate

blob.png

Immunohistochemistry analysis of parafffin-embedded mouse heart using Desmin (GB12081) at dilution of 1:500

blob.png

Immunohistochemistry analysis of parafffin-embedded rat skeletal muscle using Desmin (GB12081) at dilution of 1:500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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