Anti -Caspase-9 Mouse mAb

價格：在線咨詢

貨號：

DRF101301

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Caspase-9 mouse monoclonal
Protein full name	Caspase-9
Synonyms	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Caspase9
Isotype	IgG2a
Purity	Affinity purification
Predicted MW.	50 kDa
Observed MW.	50 kDa
Uniprot ID	Q8C3Q9

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 100-1: 200	skeletal muscle

Background

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increased in the response of cells to genotoxic stress and ABL1/c-Abl activation.

Images

Western blot analysis of Caspase-9 (GB12053) at dilution of 1: 200

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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